The demonstration at USC escalated when protesters refused to relocate and remove their tents and other prohibited items, Provost Andrew T. Guzman said in a statement posted online.
Many of the protesters "do not appear to be affiliated with USC," he said.
“Their actions have escalated to the point of confrontation and have threatened the safety of our officers and campus community,” Guzman said.
Campus gates have been closed and officials are “taking action to restrict growth of the protest and keep the rest of the campus calm,” the statement read.
“We want to be clear that we reject speech that is hateful and that causes harm to others. In these challenging times, we call on the Trojan Family to remember that every member of our community is deserving of respect, has the right to be safe on campus, take classes, and participate in other campus activities without fear of harassment or bullying. It should be everyone’s priority to treat each other with kindness and care,” Guzman continued.
“We will do all that is required to maintain the safety of every member of our community,” he said.
The scene at the University of Southern California's University Park campus has calmed after major activity erupted during a demonstration earlier on Wednesday.