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CNN One Thing

You’ve been overwhelmed with headlines all week – what's worth a closer look? One Thing takes you beyond the headlines and helps make sense of what everyone is talking about. Host David Rind talks to experts, reporters on the front lines and the real people impacted by the news about what they've learned – and why it matters. New episodes every Wednesday and Sunday.

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Trump’s Psychedelic Order: Breakthrough...or Bad Trip?
CNN One Thing
Apr 22, 2026

President Donald Trump signed an executive order on Saturday aimed at beefing up research of psychedelic drugs like ibogaine that could be used in mental health treatments. Some veterans and people who have struggled with addiction who have used ibogaine say this could be a breakthrough that could lead to wider access, but some medical experts are warning approvals shouldn’t be rushed. We hear why a leading advocate group says while it’s a good start – much more has to be done. 

For more: Trump accelerates research on psychedelic treatments and asks, ‘Can I have some?’ 

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Guests: Samantha Juan & Melissa Lavasani, Psychedelic Medicine Coalition Founder/CEO 

Host: David Rind 

Producer: Paola Ortiz 

Showrunner: Felicia Patinkin 

Editorial Support: Katherine Dillinger

Photo: Jim Watson/AFP/Getty Images