
Moderna and Merck said a late-stage trial of a personalized cancer treatment based on the mRNA technology behind Covid-19 vaccines met its goals in treating melanoma, potentially marking a major advancement in cancer care. CNN’s Meg Tirrell reports.

Moderna and Merck said a late-stage trial of a personalized cancer treatment based on the mRNA technology behind Covid-19 vaccines met its goals in treating melanoma, potentially marking a major advancement in cancer care. CNN’s Meg Tirrell reports.

The US federal debt hit a record $40 trillion on Tuesday, according to the Treasury Department. CNN’s Stephanie Yang explains what has contributed to the mounting debt and how it could impact Americans, businesses, and the government for years to come.

A pilot was killed and two state troopers were injured after a state police helicopter collided with a small plane during a training exercise at a central Pennsylvania airport Wednesday evening, officials said.

Last year, Health and Human Services Secretary RFK Jr. called mRNA vaccines for respiratory viruses unsafe for the public and the National Institutes of Health cut 22 programs totaling $500 million that targeted mRNA vaccine research for infectious diseases. Now, that same technology has succeeded in a clinical trial for treating skin cancer. CNN’s Meg Tirrell reports.

The Duke and Duchess of Sussex are planning to move back to Britain, CNN understands. Prince Harry and Meghan are said to be planning to relocate from the US later this month to a private residence outside London and reportedly have enrolled their children in British schools for the coming term, according to UK newspaper The Telegraph. CNN's Max Foster reports.

Nolan Wells, the Mississippi teen who died last month during a July 4 boating trip with a group of friends, would’ve turned 19 on Wednesday. More than six weeks later, authorities are still investigating and have given no public indication that a crime occurred. At a national prayer rally in Wells’ memory, Dr. Jamal Bryant, senior pastor of New Birth Missionary Baptist Church in Georgia, gave a keynote speech at the rally, demanding answers and a stop to the online attacks against Wells’ mother.

Nolan Wells would have turned 19 on Wednesday. More than six weeks after his death, authorities are still investigating his case and have given no indication publicly that a crime occurred. CNN's Isabel Rosales shares the letter his parents wrote their son for his birthday, shared first with CNN.

President Donald Trump revealed a new White House construction project in an impromptu tour for reporters. CNN's Betsy Klein shares new details.

A former detective who was part of a 2009 proffer agreement with Duane Davis, also known as “Keffe D,” gave his perspective on why he thinks Davis wasn’t lying about his involvement in Tupac Shakur's murder. Daryn Dupree testified that Davis admitted to his involvement during an interview with law enforcement that was originally focused on the murder of Christopher Wallace, also known as The Notorious B.I.G. Under a proffer agreement, a suspect gives potentially useful information to police under the condition that police cannot use it against them, with some exceptions.


